Hypothesis is already in use by a growing number of researchers and students in the biosciences. We are also actively looking for partners to explore the use of Hypothesis within scientific and publishing workflows, e.g., Peer Review, data curation, automated and semi-automated linking.  If you are interested in learning how Hypothesis can help support these functions, contact us.

Attention Biocurators:  Interested in controlled tagging using Hypothesis?  We have developed some prototypes that allow Hypothesis to tag with controlled vocabularies and ontologies.  We’d like your feedback.  If interested, contact us.

Also, many in the Hypothesis community are developing tools using Hypothesis that handle more specialized use cases.  See what they are up to and add your own.

Join the discussion:

Hypothesis lets researchers interactively annotate current articles.  Unlike commenting systems, the annotations are anchored to specific fragments of text. Hypothesis is also a great tool for Journal Clubs to annotate in public or using private groups.  Here are some examples:

Data and literature curation:

  • NeuroVault Database (Russ Poldrack, Stanford):  A first pass Hypothesis integration into NeuroVault, a database for sharing neuroimaging data, was deployed by graduate student Vanessa Sochat to extract neuroimaging parameters from the literature.
  • Structured literature annotation (David Kennedy, U Mass Amherst): testing Hypothesis for annotating the literature to create a “Neuromorphometry report” for the NeuroImaging Tools and Resource Clearinghouse (NITRC).
  • BioStor (Rod Page, Biodiversity Institute, Glasgow): Annotation of biodiversity geo-coordinates with Google Maps


Hypothesis is an excellent tool for teaching, allowing students and teachers to interact over scientific articles.  We have an active program in education, led by Dr. Jeremy Dean.

  • Science in the Classroom (American Association for the Advancement of Science):  Would you like to make your science more understandable? See how Hypothesis is used for annotating Science papers for educational use.

Annotate your own articles!

Did you forget a reference?  is that link broken?  Do you need to add more information to a protocol or link an article to a data set?  Use Hypothesis to provide updates on your published papers.